AXIS
Curriculum / core
/core · 3 levels · required first

Core systems

How hormones signal, how drugs behave in the body, how to read a blood panel, and how to weigh evidence. Required first.

L1Fundamentals

5 modules · exam at 85%
  1. 1.1

    How hormones signalmembers

    Steroid vs. peptide hormones, receptors, half-life, and free vs. bound hormone.

  2. 1.2

    Negative feedback loopsSimulatormembers

    The thermostat model, and what happens upstream when a hormone comes from outside.

  3. 1.3

    Pharmacology basicsmembers

    Absorption, distribution, half-life, and why the same compound behaves differently by route.

  4. 1.4

    Reading a blood panelLab readermembers

    What each common marker measures and how to spot what matters.

  5. 1.5

    Weighing evidencemembers

    Human vs. rodent data, study vs. anecdote, and how marketing borrows the language of science.

L2Applied

4 modules · exam at 85%
  1. 2.1

    Receptors in depthincoming

    Agonists, antagonists, partial agonists, and receptor up- and downregulation.

  2. 2.2

    Binding proteinsincoming

    SHBG, albumin, and why total levels can mislead.

  3. 2.3

    Lab timing and reference rangesincoming

    When to draw, how ranges are built, and why a single snapshot can mislead.

  4. 2.4

    Study designsincoming

    RCTs, cohorts, case reports, and what each can and can’t show.

L3Advanced

4 modules · exam at 85%
  1. 3.1

    Pharmacokinetics in depthHalf-lifeincoming

    Steady state, peaks and troughs, and reading a concentration curve.

  2. 3.2

    Metabolism and interactionsincoming

    Liver enzymes, interaction risk, and why combining systemic agents compounds risk.

  3. 3.3

    Reading a paper end to endincoming

    Methods, endpoints, effect sizes, and conflicts of interest.

  4. 3.4

    Working with a physicianincoming

    Building a monitoring plan and having a productive conversation with your doctor.

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